Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CDK1 | P06493 | 1/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | CDK7 | P50613 | 1/20 | 0.60 |
| ▸ | CCNH | P51946 | 1/20 | 0.60 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.60 |
| ▸ | ATIC | P31939 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571166 | 0.89 | MAPT (0.80) | CES1CYP19A1MAPTMEN1KMT2A | |
| SCHEMBL10361762 | 0.89 | MAPT (0.65) | CES1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4881670 | 0.86 | MAPT (0.66) | CES1CYP19A1MAPTALDH1A1ESR1 | |
| SCHEMBL7571133 | 0.86 | MAPT (0.63) | CYP19A1MAPTGAAMEN1KMT2A | |
| SCHEMBL23093373 | 0.86 | PRMT1 (0.62) | CES1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL5163794 | 0.86 | LMNA (0.62) | CYP19A1MAPTGAAMEN1KMT2A | |
| SCHEMBL17174222 | 0.85 | CES1 (0.66) | CES1CYP19A1MAPTGAAMEN1 | |
| SCHEMBL2474197 | 0.85 | CES1 (1.00) | CES1CYP19A1MAPTGAAMEN1 | |
| SCHEMBL6554630 | 0.85 | CES1 (1.00) | CES1CYP19A1MAPTGAAMEN1 | |
| SCHEMBL3915628 | 0.83 | HDAC1 (0.54) | CES1CYP19A1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104353-B1 | HEAT SENSITIVE RECORD MATERIAL | HODOGAYA CHEMICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| US-4482905-A | FLUORAN, BENZENESULFONAMIDE, ACID, BINDER | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | claimed |
| EP-0104353-A2 | Heat sensitive record material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-04-04 | — | — | EP | claimed |
| EP-2955173-A1 | NOVEL 1,2-BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-12-16 | — | — | EP | disclosed |
| WO-2002078970-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | disclosed |