Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563692 | 1.00 | S1PR1 (0.38) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7563687 | 1.00 | S1PR1 (0.38) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7558492 | 0.85 | MAPK1 (0.43) | PPARGPPARAHTR1AHTR1DHTR1B | |
| SCHEMBL7519021 | 0.81 | S1PR1 (0.37) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7519026 | 0.81 | S1PR1 (0.37) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7519018 | 0.81 | S1PR1 (0.37) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7560255 | 0.80 | HTR2A (0.46) | HTR1AHTR1DHTR1BALDH1A1LMNA | |
| SCHEMBL7928544 | 0.77 | RARB (0.42) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7557453 | 0.77 | RARB (0.46) | HTR1AHTR1DHTR1BMEN1USP2 | |
| SCHEMBL13310859 | 0.75 | S1PR1 (0.52) | S1PR1S1PR4S1PR5S1PR2S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946473-B1 | FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECHNOLOGY GMBH (DE) | 2002-07-31 | — | — | EP | disclosed |
| US-6168838-B1 | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-01-02 | — | — | US | disclosed |