Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519021 | 1.00 | S1PR1 (0.37) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7519026 | 1.00 | S1PR1 (0.37) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7528065 | 0.86 | MAPK1 (0.41) | TLR8MEN1USP2ALDH1A1LMNA | |
| SCHEMBL7563692 | 0.81 | S1PR1 (0.38) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7563682 | 0.81 | S1PR1 (0.38) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7563687 | 0.81 | S1PR1 (0.38) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL7515612 | 0.76 | CYP3A4 (0.41) | PLA2G4AMEN1USP2ALDH1A1LMNA | |
| SCHEMBL7517995 | 0.76 | CYP3A4 (0.49) | TLR8PPARAMEN1USP2ALDH1A1 | |
| SCHEMBL9001598 | 0.74 | MAPT (0.44) | S1PR1S1PR4S1PR5S1PR2S1PR3 | |
| SCHEMBL13310859 | 0.74 | S1PR1 (0.52) | S1PR1S1PR4S1PR5S1PR2S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946513-B1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-01-30 | — | — | EP | disclosed |
| US-6120703-A | Derivatives of 6-fluorophenanthridine for liquid crystal mixtures | AVENTIS RESEARCH & TECHNOLOGIES DEUTSCHLAND GMBH & CO. KG (DE) | 2000-09-19 | — | — | US | disclosed |