Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558787 | 0.85 | RARB (0.42) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL3158048 | 0.80 | RARB (0.46) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL8024024 | 0.79 | RARB (0.51) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL13310859 | 0.79 | S1PR1 (0.52) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL8023518 | 0.79 | S1PR1 (0.52) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL3154328 | 0.78 | RARB (0.44) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL3157715 | 0.78 | RARB (0.44) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL7563687 | 0.77 | S1PR1 (0.38) | S1PR1MEN1ALDH1A1KMT2AS1PR4 | |
| SCHEMBL7563682 | 0.77 | S1PR1 (0.38) | S1PR1MEN1ALDH1A1KMT2AS1PR4 | |
| SCHEMBL7563692 | 0.77 | S1PR1 (0.38) | S1PR1MEN1ALDH1A1KMT2AS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946474-B1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-07 | — | — | EP | disclosed |
| US-6159561-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |