Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238668 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HTTL3MBTL1MLYCDTSHR | |
| SCHEMBL892545 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HTTL3MBTL1MLYCDTSHR | |
| SCHEMBL14261164 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTL3MBTL1MLYCDTSHR | |
| SCHEMBL1091380 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HTTL3MBTL1MLYCDPOLB | |
| SCHEMBL9548360 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTL3MBTL1MLYCDTSHR | |
| SCHEMBL9296882 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTL3MBTL1MLYCDTSHR | |
| SCHEMBL892104 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HTTL3MBTL1MLYCDTSHR | |
| SCHEMBL15142568 | 0.75 | MLYCD (0.53) | ALDH1A1HTTL3MBTL1MLYCD | |
| SCHEMBL13060580 | 0.75 | MLYCD (0.50) | ALDH1A1HTTL3MBTL1MLYCD | |
| SCHEMBL13282708 | 0.74 | ALDH1A1 (0.43) | ALDH1A1HTTL3MBTL1MLYCDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017844-B1 | COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES AND CANCER | AC BIOSCIENCE SA (CH) | 2024-01-24 | — | — | EP | disclosed |
| US-20220306587-A1 | COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES AND CANCER | AC BIOSCIENCE SA (CH) | 2022-09-29 | — | — | US | disclosed |
| EP-4017844-A1 | COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES AND CANCER | AC BioScience SA (CH) | 2022-06-29 | — | — | EP | disclosed |
| CN-114555567-A | Compounds and their use for the treatment of infectious diseases and cancer | AC生命科学有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021032857-A1 | COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES AND CANCER | AC BIOSCIENCE SA (CH) | 2021-02-25 | — | — | WO | disclosed |
| WO-2021032857-A1 | COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES AND CANCER | AC BIOSCIENCE SA (CH) | 2021-02-25 | — | — | WO | disclosed |
| EP-0957097-B1 | Process for the preparation pf 3-isoxazolecarboxylic acid | SHIONOGI & CO (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-0739885-B1 | PROCESS FOR PRODUCING 3-ISOXAZOLECARBOXYLIC ACID | SHIONOGI & CO (JP) | 2000-04-19 | — | — | EP | disclosed |
| EP-0957097-A1 | Process for the preparation pf 3-isoxazolecarboxylic acid | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5760244-A | Process for the preparation of 3-isoxazolecarboxylic acid | SHIONOGI & CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5696271-A | Process for the preparation of 3-isoxazolecarboxylic acid | SHIONOGI & CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0739885-A1 | PROCESS FOR PRODUCING 3-ISOXAZOLECARBOXYLIC ACID | SHIONOGI & CO., LTD. (JP) | 1996-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306587-A1 | COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES AND CANCER | SGPL1, SPHK1, S1PR1 | ALDH1A1 381/4885HTT 4168/4885L3MBTL1 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.