Kresoxim-Methyl

Kresoxim-Methyl

SCHEMBL7563778

CO/C(C)=C(/C(=O)O)c1ccccc1Oc1cc(Oc2ccccc2C#N)ncn1.CO/N=C(/C(=O)OC)c1ccccc1COc1ccccc1C

nearest known ligand 0.57

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.43
PIN1 Q13526 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
SGMS2 Q8NHU3 1/20 0.33
MET P08581 1/20 0.33
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azoxystrobin SCHEMBL3785319 0.86 HIF1A (0.43) HIF1AALDH1A1
Kresoxim-Methyl SCHEMBL8318345 0.86 HIF1A (0.38) HIF1ASGMS2
SCHEMBL2837438 0.82 PIN1 (0.46) PIN1ALDH1A1HPGD
SCHEMBL205372 0.82 PIN1 (0.46) PIN1ALDH1A1HPGD
SCHEMBL6447259 0.81 HIF1A (0.41) HIF1APIN1ALDH1A1HPGD
SCHEMBL3456741 0.77 PIN1 (0.39) PIN1ALDH1A1HPGD
SCHEMBL7633885 0.77 SMN1; SMN2 (0.42) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL203796 0.77 SMN1; SMN2 (0.42) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
SCHEMBL899340 0.76 KDM4E (0.40) PIN1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL899337 0.76 KDM4E (0.40) PIN1ALDH1A1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934368-B1 ANTIFOULING PAINT BAYER AG (DE) 2002-03-13 EP disclosed
EP-0934368-A1 ANTIFOULING PAINT BAYER AG (DE) 1999-08-11 EP disclosed
WO-1998017733-A1 ANTIFOULING PAINT BAYER AKTIENGESELLSCHAFT (DE) 1998-04-30 WO disclosed