Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PPIB | P23284 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566004 | 0.78 | GRIA1 (0.43) | ALDH1A1SMN1; SMN2KDM4EMAPTGRIA1 | |
| SCHEMBL10556095 | 0.76 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL7564514 | 0.74 | GRIA1 (0.62) | ALDH1A1SMN1; SMN2KDM4EMAPTGRIA1 | |
| SCHEMBL27434788 | 0.73 | BCL9 (0.31) | ALDH1A1 | |
| SCHEMBL7565564 | 0.73 | GRIA1 (0.45) | ALDH1A1SMN1; SMN2KDM4EMAPTGRIA1 | |
| SCHEMBL3147669 | 0.73 | PPID (0.50) | ALDH1A1SMN1; SMN2KDM4EMAPTGRIA1 | |
| SCHEMBL13222646 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2KDM4EMAPTGRIA1 | |
| SCHEMBL7567175 | 0.71 | GRIA1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMAPTGRIA1 | |
| SCHEMBL13244223 | 0.69 | MEN1 (0.49) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL8337648 | 0.69 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EMAPTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1125818-C | Amino acid derivatives of substituted quinoxaline 2, 3 -dione derivativesa as glutamate receptor antagonists | WARNER LAMBERT CO (US) | 2003-10-29 | — | — | CN | disclosed |
| EP-0832074-B1 | AMINO ACID DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2002-09-04 | — | — | EP | disclosed |
| CN-1187190-A | Amino acid derivatives of substituted quinoxaline 2, 3-dione derivatives as glutamate receptor antagonists | WARNER LAMBERT CO (US) | 1998-07-08 | — | — | CN | disclosed |
| US-5614508-A | ANTIISCHEMIC AGENTS, ALZHEIMERS, STROKE OR NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1996040649-A1 | AMINO ACID DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |