SCHEMBL7563897

SCHEMBL7563897

O=C1C(Cl)=C(Cl)C(=O)N1Cc1ccc(Cl)cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
POLB P06746 1/20 0.50
CYP2A13 Q16696 1/20 0.47
NPC1 O15118 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 1/20 0.47
PTPN1 P18031 1/20 0.47
IDO1 P14902 1/20 0.47
SIGMAR1 Q99720 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.46
P2RX7 Q99572 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11081773 0.84 MAPT (0.58) CA12CA1CA2CA9LMNA
SCHEMBL11841629 0.84 CA12 (0.51) CA12CA1CA2CA9LMNA
SCHEMBL4749291 0.81 CA12 (0.51) CA12CA1CA2CA9LMNA
SCHEMBL7559102 0.77 SMN1; SMN2 (0.55) LMNASMN1; SMN2POLBHTTRAB9A
SCHEMBL8144393 0.75 PTPN1 (0.48) CA12CA1CA2CA9POLB
SCHEMBL30774282 0.75 CES1 (0.67) CA12CA1CA2CA9LMNA
SCHEMBL18974316 0.75 CES1 (0.67) CA12CA1CA2CA9LMNA
SCHEMBL4746784 0.74 CA12 (0.46) CA12CA1CA2CA9LMNA
SCHEMBL7558814 0.74 CES2 (0.53) CA12CA1CA2CA9LMNA
SCHEMBL5468385 0.74 GSK3A (0.54) CA12CA1CA2CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108415221-B Photosensitive resin composition and application thereof 奇美实业股份有限公司 2023-07-28 CN disclosed
CN-106444285-B Photosensitive resin composition for color filter and application thereof 奇美实业股份有限公司 2021-09-10 CN disclosed
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
EP-0877061-A1 TRIPHENYLBORANE-ROSIN AMINE ADDUCT AND USE OF THE SAME Yoshitomi Fine Chemicals, Ltd. (JP) 1998-11-11 EP disclosed