Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563897 | 0.81 | CA12 (0.51) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11841629 | 0.77 | CA12 (0.51) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11081773 | 0.77 | MAPT (0.58) | CA12CA1CA2CA9LMNA | |
| SCHEMBL4802311 | 0.77 | PTGS1 (0.61) | LMNASMN1; SMN2MGLLFAAHPOLB | |
| SCHEMBL18974316 | 0.75 | CES1 (0.67) | CA12CA1CA2CA9LMNA | |
| SCHEMBL30774282 | 0.75 | CES1 (0.67) | CA12CA1CA2CA9LMNA | |
| SCHEMBL7218376 | 0.74 | MGLL (0.82) | CA12CA1CA2CA9MGLL | |
| SCHEMBL5468385 | 0.74 | GSK3A (0.54) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8144393 | 0.72 | PTPN1 (0.48) | CA12CA1CA2CA9POLB | |
| SCHEMBL2179428 | 0.71 | DBH (0.53) | LMNASMN1; SMN2CYP2A13NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124518-A1 | OXO-DIHYDROISOINDOLE SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | disclosed |
| US-20060142487-A1 | Process for the production of a transparent rubber-modified monovinylidene aromatic resin | CHI-MEI CORPORATION (TW) | 2006-06-29 | — | — | US | disclosed |
| US-20040230003-A1 | Transparent rubber-modified monovinylidene aromatic resin | CHI MEI CORPORATION (TW) | 2004-11-18 | — | — | US | disclosed |