Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40302 | 0.88 | MEN1 (0.45) | NPSR1RXFP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1830325 | 0.87 | MEN1 (0.44) | NPSR1RXFP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL5785897 | 0.87 | MEN1 (0.44) | NPSR1RXFP1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7826245 | 0.87 | NPSR1 (0.39) | NPSR1RXFP1TSHRALDH1A1LMNA | |
| SCHEMBL7829858 | 0.80 | MAPT (0.48) | TSHRALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL7750180 | 0.80 | MEN1 (0.45) | NPSR1RXFP1TSHRALDH1A1LMNA | |
| SCHEMBL2485564 | 0.77 | MEN1 (0.45) | NPSR1RXFP1TSHRALDH1A1HPGD | |
| SCHEMBL7818937 | 0.76 | PTGS2 (0.44) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL7556606 | 0.76 | MEN1 (0.43) | NPSR1RXFP1TSHRALDH1A1LMNA | |
| SCHEMBL321543 | 0.76 | MEN1 (0.45) | NPSR1RXFP1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095021-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-02 | — | — | EP | claimed |
| WO-2000003991-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | claimed |
| EP-1224172-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | Active Biotech AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030758-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2001-05-03 | — | — | WO | disclosed |
| EP-1095021-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000003991-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |