Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830325 | 0.87 | MEN1 (0.44) | MAPTTP53ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5785897 | 0.87 | MEN1 (0.44) | MAPTTP53ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7564008 | 0.80 | NPSR1 (0.40) | MAPTTP53ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7556725 | 0.80 | KMT2A (0.43) | MAPTTP53ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7828963 | 0.78 | MAPT (0.38) | MAPTALDH1A1TSHRHTT | |
| SCHEMBL7556606 | 0.76 | MEN1 (0.43) | MAPTTP53ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7557817 | 0.76 | GPBAR1 (0.40) | — | |
| SCHEMBL7558468 | 0.76 | GPBAR1 (0.38) | MAPTKDM4ESMN1; SMN2POLB | |
| SCHEMBL7750180 | 0.75 | MEN1 (0.45) | MAPTTP53ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7559771 | 0.75 | MEN1 (0.50) | MAPTTP53ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095021-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000003991-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |