Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 5/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568211 | 0.91 | AOX1 (0.53) | AOX1HDAC1HDAC6RAD52ALDH1A1 | |
| SCHEMBL8415065 | 0.88 | AOX1 (0.47) | AOX1HDAC1HDAC6RAD52TACR3 | |
| SCHEMBL8415046 | 0.88 | AOX1 (0.53) | AOX1HDAC1HDAC6RAD52TACR3 | |
| SCHEMBL8414087 | 0.87 | AOX1 (0.46) | AOX1HDAC1HDAC6RAD52TACR3 | |
| SCHEMBL7572699 | 0.87 | AOX1 (0.46) | AOX1HDAC1HDAC6RAD52TACR3 | |
| SCHEMBL7567204 | 0.85 | NPC1 (0.47) | AOX1RAD52ALDH1A1KDM4EGAA | |
| SCHEMBL7565768 | 0.84 | AOX1 (0.44) | AOX1HDAC1HDAC6RAD52 | |
| SCHEMBL7567237 | 0.84 | AOX1 (0.44) | AOX1HDAC1HDAC6RAD52ALDH1A1 | |
| SCHEMBL7564033 | 0.84 | HDAC1 (0.40) | AOX1HDAC1HDAC6TACR3ALDH1A1 | |
| SCHEMBL7566415 | 0.82 | RAD52 (0.47) | AOX1HDAC1HDAC6RAD52TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |