Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KLRK1 | P26718 | 4/20 | 0.39 |
| ▸ | MICA | Q29983 | 4/20 | 0.39 |
| ▸ | RAET1L | Q5VY80 | 4/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | NCS1 | P62166 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572699 | 0.86 | AOX1 (0.46) | AOX1RAD52HDAC1HDAC6 | |
| SCHEMBL8415065 | 0.85 | AOX1 (0.47) | AOX1RAD52HDAC1HDAC6 | |
| SCHEMBL7565752 | 0.85 | FGFR4 (0.38) | AOX1RXFP1KLRK1MICARAET1L | |
| SCHEMBL8415046 | 0.85 | AOX1 (0.53) | AOX1RAD52HDAC1HDAC6 | |
| SCHEMBL7564042 | 0.84 | AOX1 (0.46) | AOX1RAD52HDAC1HDAC6 | |
| SCHEMBL8414087 | 0.84 | AOX1 (0.46) | AOX1RXFP1TAS1R3TAS1R1RAD52 | |
| SCHEMBL7567803 | 0.84 | CTSS (0.46) | AOX1HDAC11RAD52HDAC1HDAC6 | |
| SCHEMBL7570996 | 0.82 | AOX1 (0.52) | AOX1RAD52HDAC1HDAC6KCNA5 | |
| SCHEMBL7567204 | 0.82 | NPC1 (0.47) | AOX1RAD52 | |
| SCHEMBL7024935 | 0.82 | AOX1 (0.66) | AOX1RAD52HDAC1HDAC6PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |