Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 9/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 9/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CCR9 | P51686 | 4/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572137 | 1.00 | GAA (0.42) | GAAKMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL7607342 | 0.91 | CCR9 (0.43) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7588736 | 0.89 | CCR9 (0.45) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7572678 | 0.88 | GSK3B (0.42) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7586565 | 0.87 | PTPN2 (0.41) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7565871 | 0.86 | GSK3B (0.46) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7572797 | 0.84 | ACLY (0.49) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7569198 | 0.83 | CCR9 (0.44) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7567130 | 0.82 | GSK3B (0.45) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7590087 | 0.82 | GSK3B (0.44) | KMT2APTPN2PTPN1PTPN5HSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |