Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 8/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 8/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.41 |
| ▸ | TST | Q16762 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CCR9 | P51686 | 4/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573760 | 0.89 | ALDH1A1 (0.47) | CCR9EIF4EALDH1A1MAPTCRHBP | |
| SCHEMBL7607342 | 0.89 | CCR9 (0.43) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7588736 | 0.87 | CCR9 (0.45) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7572137 | 0.87 | GAA (0.42) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7564229 | 0.87 | GAA (0.42) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7572678 | 0.85 | GSK3B (0.42) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7565871 | 0.84 | GSK3B (0.46) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7567847 | 0.82 | ACLY (0.46) | GSK3BALDH1A1MAPT | |
| SCHEMBL7572797 | 0.81 | ACLY (0.49) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL7569198 | 0.81 | CCR9 (0.44) | PTPN2PTPN1PTPN5HSPD1HSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |