Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | USP8 | P40818 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566650 | 0.86 | ACLY (0.57) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7573002 | 0.84 | ACLY (0.59) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7566442 | 0.81 | ACLY (0.48) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7567344 | 0.81 | ACLY (0.48) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7571135 | 0.81 | PTGES2 (0.48) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7568243 | 0.81 | ACLY (0.48) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7573023 | 0.81 | CCR2 (0.48) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7571988 | 0.81 | ACLY (0.48) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7567847 | 0.79 | ACLY (0.46) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL7572073 | 0.77 | ACLY (0.44) | ACLYHDAC6GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |