SCHEMBL7564408

SCHEMBL7564408

CCCOCCOc1cccc(F)n1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 2/20 0.41
FFAR4 Q5NUL3 1/20 0.35
NCF1 P14598 5/20 0.34
TSHR P16473 1/20 0.34
RARB P10826 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565905 0.90 NCF1 (0.42) HTR7NCF1
SCHEMBL8504109 0.81 MCHR1 (0.43) HTR7TSHR
SCHEMBL113568 0.81 HTR7 (0.44) HTR7TSHR
SCHEMBL25097014 0.78 MAPK8 (0.49) HTR7FFAR4
SCHEMBL2521218 0.76 HTR7 (0.47) HTR7FFAR4TSHR
SCHEMBL16883985 0.74 ABCG2 (0.39) HTR7NCF1RARB
Hydrochloric Acid SCHEMBL19743607 0.74 KDM4E (0.44) HTR7
SCHEMBL13196833 0.72 MAPT (0.55) NCF1
SCHEMBL9271670 0.72 GPBAR1 (0.38) HTR7FFAR4TSHR
SCHEMBL6743 0.72 HTR7 (0.67) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020115865-A1 2-methoxyimino-2- (pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring CANADA EMILY J (US) 2002-08-22 US disclosed
US-6432990-B1 FUNGICIDES DOW AGROSCIENCES LLC 2002-08-13 US disclosed
US-6369083-B1 2-methoxyimino-2 (pyrinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring DOW AGROSCIENCES LLC 2002-04-09 US disclosed
WO-2000015635-A1 2-METHOXYIMINO -2-(PYRIDINYLOXYMETHYL) PHENYL ACETAMIDES USEFUL AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2000-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115865-A1 2-methoxyimino-2- (pyridinyloxymethyl) phenyl acetamides with polyether derivatives on the pyridine ring AADAC, MIDEAS, CNPY2 HTR7 3007/4885FFAR4 3137/4885NCF1 4617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.