SCHEMBL7564529

SCHEMBL7564529

CCN1C(=O)/C(=N/O)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
ALDH1A1 P00352 11/20 0.53
HPGD P15428 1/20 0.53
CASP1 P29466 1/20 0.53
MPI P34949 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 2/20 0.51
MAPT P10636 4/20 0.50
TP53 P04637 1/20 0.50
KDM4E B2RXH2 1/20 0.50
HTT P42858 1/20 0.50
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP1B1 Q16678 1/20 0.45
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564533 1.00 CA12 (0.56) CA12CA2CA9ALDH1A1HPGD
SCHEMBL9301105 0.87 ALDH1A1 (0.53) CA12CA2CA9ALDH1A1HPGD
SCHEMBL7589906 0.87 ALDH1A1 (0.53) CA12CA2CA9ALDH1A1HPGD
SCHEMBL7611054 0.81 ALDH1A1 (0.66) CA12CA2CA9ALDH1A1HSD17B10
SCHEMBL7611051 0.81 ALDH1A1 (0.66) CA12CA2CA9ALDH1A1HSD17B10
SCHEMBL29072528 0.81 CA12 (0.71) CA12CA2CA9ALDH1A1HPGD
SCHEMBL18188970 0.80 CA12 (0.50) CA12CA2CA9ALDH1A1HPGD
SCHEMBL18188968 0.80 CA12 (0.50) CA12CA2CA9ALDH1A1HPGD
SCHEMBL6317939 0.80 ALDH1A1 (0.54) CA12CA2CA9ALDH1A1HSD17B10
SCHEMBL6599293 0.80 ALDH1A1 (0.43) CA12CA2CA9ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1206241-A1 METHODS OF LIGHTENING KERATINOUS TISSUE BY TOPICAL APPLICATION OF OXIME COMPOUND CONTAINING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP disclosed
WO-2001013882-A1 METHODS OF LIGHTENING KERATINOUS TISSUE BY TOPICAL APPLICATION OF OXIME COMPOUND CONTAINING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO disclosed
US-5364617-A Protection from solar radiation, chelate with iron in body and reduce its ability to catalyze formation of oxygen free radicals THE PROCTER & GAMBLE COMPANY (US) 1994-11-15 US disclosed
EP-0611301-A1 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1994-08-24 EP disclosed
EP-0611301-A4 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS. PROCTER & GAMBLE (US) 1993-03-01 EP disclosed
WO-1991016034-A1 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1991-10-31 WO disclosed