SCHEMBL7589906

SCHEMBL7589906

CCCN1C(=O)/C(=N\O)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH2 P05091 1/20 0.51
ALDH3A1 P30838 1/20 0.51
ACE P12821 1/20 0.51
CDC25A P30304 8/20 0.50
CES1 P23141 3/20 0.50
LMNA P02545 1/20 0.50
KMT2A Q03164 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
MAPT P10636 2/20 0.49
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
BCHE P06276 1/20 0.49
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301105 1.00 ALDH1A1 (0.53) ALDH1A1KDM4EALDH2ALDH3A1ACE
SCHEMBL7564533 0.87 CA12 (0.56) ALDH1A1KDM4EALDH2ALDH3A1CDC25A
SCHEMBL7564529 0.87 CA12 (0.56) ALDH1A1KDM4EALDH2ALDH3A1CDC25A
SCHEMBL18200162 0.81 ACE (0.52) ALDH1A1KDM4EALDH2ALDH3A1ACE
SCHEMBL18189107 0.81 ACE (0.52) ALDH1A1KDM4EALDH2ALDH3A1ACE
SCHEMBL18189109 0.81 ACE (0.52) ALDH1A1KDM4EALDH2ALDH3A1ACE
SCHEMBL19297268 0.81 ALDH1A1 (0.62) ALDH1A1KDM4EALDH2ALDH3A1CDC25A
SCHEMBL9587266 0.80 CDC25A (0.72) ALDH1A1ALDH2ALDH3A1CDC25ACES1
SCHEMBL18189117 0.80 ACE (0.51) ALDH1A1KDM4EALDH2ALDH3A1ACE
SCHEMBL20138374 0.80 ACE (0.51) ALDH1A1KDM4EALDH2ALDH3A1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1206241-A1 METHODS OF LIGHTENING KERATINOUS TISSUE BY TOPICAL APPLICATION OF OXIME COMPOUND CONTAINING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP disclosed
WO-2001013882-A1 METHODS OF LIGHTENING KERATINOUS TISSUE BY TOPICAL APPLICATION OF OXIME COMPOUND CONTAINING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO disclosed
US-5364617-A Protection from solar radiation, chelate with iron in body and reduce its ability to catalyze formation of oxygen free radicals THE PROCTER & GAMBLE COMPANY (US) 1994-11-15 US disclosed
EP-0611301-A1 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1994-08-24 EP disclosed
EP-0611301-A4 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS. PROCTER & GAMBLE (US) 1993-03-01 EP disclosed
WO-1991016034-A1 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1991-10-31 WO disclosed