Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 8/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2273253 | 0.80 | NSD2 (0.65) | NPY1RNSD2CASP6G6PDHSP90AA1 | |
| SCHEMBL7566187 | 0.77 | L3MBTL1 (0.58) | HSP90AA1MAPTIDO1L3MBTL1NPC1 | |
| SCHEMBL7996851 | 0.77 | L3MBTL1 (0.58) | HSP90AA1MAPTIDO1L3MBTL1NPC1 | |
| SCHEMBL7566133 | 0.76 | ALDH1A1 (0.56) | CASP6HSP90AA1HSP90AB1MEN1MAPT | |
| SCHEMBL19009450 | 0.72 | NPC1 (0.47) | HSP90AA1MAPTALDH1A1IDO1L3MBTL1 | |
| SCHEMBL7567056 | 0.71 | MAPT (0.46) | NPY1RHSP90AA1HSP90AB1MEN1MAPT | |
| SCHEMBL2273020 | 0.70 | NSD2 (0.59) | NPY1RNSD2CASP6G6PDHSP90AA1 | |
| SCHEMBL14347701 | 0.70 | KDM4E (0.52) | HSP90AA1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29661788 | 0.70 | KDM4E (0.52) | HSP90AA1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL5447339 | 0.69 | HSP90AA1 (0.59) | NPY1RNSD2CASP6G6PDHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813608-B1 | OSMIUM-CONTAINING REDOX MEDIATOR | ROCHE DIAGNOSTICS CORP (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-0813608-A4 | OSMIUM-CONTAINING REDOX MEDIATOR | ROCHE DIAGNOSTICS CORP (US) | 2000-02-09 | — | — | EP | disclosed |
| US-5846702-A | Reagent including an osmium-containing redox mediator | BOEHRINGER MANNHEIM CORPORATION (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0813608-A1 | OSMIUM-CONTAINING REDOX MEDIATOR | BOEHRINGER MANNHEIM CORPORATION (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5589326-A | FOR ELECTROCHEMICAL BIOSENSORS | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-12-31 | — | — | US | disclosed |
| WO-1996025514-A1 | OSMIUM-CONTAINING REDOX MEDIATOR | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-08-22 | — | — | WO | disclosed |