Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567199 | 0.88 | MEN1 (0.55) | HDAC1HDAC6AOX1MEN1KMT2A | |
| SCHEMBL7564809 | 0.80 | AOX1 (0.60) | HDAC1HDAC6AOX1MEN1KMT2A | |
| SCHEMBL8414264 | 0.79 | AOX1 (0.61) | HDAC1HDAC6AOX1KMT2AKDM4E | |
| SCHEMBL7572168 | 0.78 | AOX1 (0.57) | HDAC1HDAC6AOX1MEN1KMT2A | |
| SCHEMBL7570661 | 0.78 | AOX1 (0.57) | HDAC1HDAC6AOX1KDM4EALDH1A1 | |
| SCHEMBL8413595 | 0.78 | AOX1 (0.54) | HDAC1HDAC6AOX1TSHRRAD52 | |
| SCHEMBL7568147 | 0.78 | KDM4E (0.48) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7573617 | 0.78 | HDAC1 (0.49) | HDAC1HDAC6AOX1KMT2AKDM4E | |
| SCHEMBL8624357 | 0.78 | HDAC1 (0.49) | HDAC1HDAC6AOX1MEN1KMT2A | |
| SCHEMBL7567204 | 0.76 | NPC1 (0.47) | AOX1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |