SCHEMBL7564877

SCHEMBL7564877

CCCOC(=O)Nc1cccc(NC(=O)O)c1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.71
MAPK1 P28482 4/20 0.64
LMNA P02545 2/20 0.64
MAPT P10636 1/20 0.64
HSD17B10 Q99714 1/20 0.64
RAB9A P51151 5/20 0.59
SMN1; SMN2 Q16637 5/20 0.59
NPC1 O15118 5/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
ALDH1A1 P00352 3/20 0.54
MGLL Q99685 1/20 0.52
HTT P42858 1/20 0.52
F2R P25116 1/20 0.52
EPHX2 P34913 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564873 0.94 HPGD (0.79) HPGDMAPK1LMNAMAPTHSD17B10
SCHEMBL7565917 0.91 RAB9A (0.72) HPGDMAPK1LMNAMAPTHSD17B10
SCHEMBL21526644 0.89 HPGD (0.73) HPGDMAPK1LMNAMAPTHSD17B10
SCHEMBL7565151 0.89 MAPK1 (0.79) HPGDMAPK1LMNAMAPTHSD17B10
SCHEMBL10191988 0.88 HPGD (0.71) HPGDMAPK1LMNAMAPTHSD17B10
SCHEMBL7562461 0.87 SMN1; SMN2 (0.69) HPGDMAPK1MAPTRAB9ASMN1; SMN2
SCHEMBL3229905 0.85 HPGD (0.67) HPGDMAPK1LMNAMAPTHSD17B10
SCHEMBL12927953 0.85 HPGD (0.68) HPGDMAPK1LMNAMAPTHSD17B10
SCHEMBL11431792 0.84 HPGD (0.71) HPGDMAPK1LMNAMAPTHSD17B10
SCHEMBL7565913 0.84 RAB9A (0.81) HPGDMAPK1LMNAMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0855393-B1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KK (JP) 2002-08-14 EP disclosed
US-5922882-A ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1999-07-13 US disclosed
EP-0855393-A1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1998-07-29 EP disclosed