SCHEMBL7565059

SCHEMBL7565059

[O]c1ccc(C(F)(F)F)c(C(=O)O)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.42
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
CES2 O00748 2/20 0.37
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
KMO O15229 3/20 0.35
SRD5A2 P31213 1/20 0.34
ASPH Q12797 1/20 0.34
DPP4 P27487 1/20 0.33
ANO1 Q5XXA6 1/20 0.33
CLCN2 P51788 1/20 0.33
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19585735 0.79 DAO (0.42) DAOALDH1A1HPGDCES2RXRA
SCHEMBL4849605 0.77 DAO (0.44) DAOALDH1A1HPGDCES2RXRA
SCHEMBL504216 0.76 CA12 (0.46) DAOALDH1A1HPGDRXRARXRB
SCHEMBL187015 0.73 SELL (0.42) DAOALDH1A1HPGDCES2RXRA
SCHEMBL7929893 0.73 DAO (0.41) DAOALDH1A1HPGDCES2RXRA
SCHEMBL28636307 0.73 ALDH1A1 (0.45) DAOALDH1A1HPGDKMOPLK1
SCHEMBL23908702 0.72 ALDH1A1 (0.51) ALDH1A1HPGDKMOLMNAGAA
SCHEMBL979367 0.72 CLCN2 (0.47) DAOALDH1A1HPGDKMODPP4
SCHEMBL7927678 0.72 DPP4 (0.44) DAOALDH1A1HPGDKMODPP4
SCHEMBL7565055 0.72 ALDH1A1 (0.41) DAOALDH1A1HPGDCES2RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1232851-A2 Process for producing polyimide platy object Central Glass Company, Limited (JP) 2002-08-21 EP disclosed