Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19585735 | 0.86 | DAO (0.42) | DAOKMOCES2CES1KIF11 | |
| SCHEMBL936925 | 0.84 | DAO (0.46) | DAOKMOCES2CES1KIF11 | |
| SCHEMBL7918733 | 0.82 | KIF11 (0.37) | DAOCES2CES1KIF11ALDH1A1 | |
| SCHEMBL7927678 | 0.82 | DPP4 (0.44) | DAOKMOALDH1A1HPGDANO1 | |
| SCHEMBL29570683 | 0.81 | TAS2R14 (0.39) | DAOCES2ALDH1A1HPGDNOTUM | |
| SCHEMBL7932556 | 0.81 | KMO (0.40) | DAOKMOKIF11ALDH1A1HPGD | |
| SCHEMBL7932574 | 0.79 | NOTUM (0.49) | CES2CES1KIF11ARNOTUM | |
| SCHEMBL29196720 | 0.79 | LMNA (0.47) | KIF11NOTUM | |
| SCHEMBL31258574 | 0.78 | CES2 (0.47) | CES2CES1ALDH1A1 | |
| SCHEMBL365563 | 0.78 | CES2 (0.47) | CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847977-B1 | 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6054605-A | CHEMICAL INTERMEDIATE FOR DRUGS, PESTICIDES | NIPPON SODA CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| US-6054624-A | USEFUL AS THE STARTING MATERIALS FOR PRODUCING PESTICIDES, DRUGS AND THE LIKE | NIPPON SODA CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0847977-A1 | 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | NIPPON SODA CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |