Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 12/20 | 0.41 |
| ▸ | RARB | P10826 | 11/20 | 0.41 |
| ▸ | RXRA | P19793 | 11/20 | 0.41 |
| ▸ | RARA | P10276 | 9/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 8/20 | 0.31 |
| ▸ | RXRG | P48443 | 7/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476357 | 1.00 | RARG (0.41) | RARGRARBRXRARARAPTGS1 | |
| SCHEMBL6876614 | 0.77 | RARB (0.46) | RARGRARBRXRARARACYP26A1 | |
| SCHEMBL6882513 | 0.74 | CYP3A4 (0.39) | RARGRARBRXRARARARXRB | |
| SCHEMBL7560513 | 0.74 | RXRA (0.40) | RARGRARBRXRARARARXRB | |
| SCHEMBL7560510 | 0.74 | RXRA (0.40) | RARGRARBRXRARARARXRB | |
| SCHEMBL7560853 | 0.74 | RXRA (0.48) | RARGRARBRXRARARARXRB | |
| SCHEMBL6476890 | 0.74 | RXRA (0.48) | RARGRARBRXRARARARXRB | |
| SCHEMBL6882515 | 0.73 | RARB (0.43) | RARGRARBRARAPTGS1PTGS2 | |
| SCHEMBL7045571 | 0.72 | PTGS1 (0.34) | PTGS1PTGS2 | |
| SCHEMBL6476360 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | claimed |