Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497721 | 0.90 | PNMT (0.48) | PNMTPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL5497718 | 0.85 | PNMT (0.53) | KMT2APNMTEPHX2NPC1RAB9A | |
| SCHEMBL6849876 | 0.83 | PNMT (0.50) | PNMTPTGER1PTGER4PTGER3PTGER2 | |
| Methyl Alcohol SCHEMBL7565244 | 0.81 | PNMT (0.41) | KMT2APNMTHTR2CSLC6A3EPHX2 | |
| SCHEMBL7559894 | 0.80 | PNMT (0.39) | PNMTPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7565247 | 0.78 | KMT2A (0.58) | KMT2AEPHX2NPC1FFAR4EGFR | |
| SCHEMBL4059193 | 0.78 | PNMT (0.50) | KMT2APNMTHTR2CPTGER1PTGER4 | |
| SCHEMBL4059189 | 0.77 | PNMT (0.54) | KMT2APNMTHTR2CNPC1RAB9A | |
| SCHEMBL27429983 | 0.77 | PNMT (0.52) | PNMTEPHX2NPC1RAB9AALDH1A1 | |
| SCHEMBL1830397 | 0.77 | PNMT (0.57) | KMT2APNMTHTR2CPTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225918-A2 | CONJUGATES USEFUL IN THE TREATMENT OF PROSTATE CANCER | Merck & Co., Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001028593-A2 | CONJUGATES USEFUL IN THE TREATMENT OF PROSTATE CANCER | MERCK & CO., INC. (US) | 2001-04-26 | — | — | WO | disclosed |