Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855670 | 0.81 | AGXT (0.52) | AGXTCA1CA2CA9KCNH2 | |
| SCHEMBL31084123 | 0.80 | IDO1 (0.33) | IDO1 | |
| SCHEMBL958300 | 0.75 | AGXT (0.64) | AGXTCA1CA2CA9KCNH2 | |
| SCHEMBL11639552 | 0.72 | AGXT (0.50) | AGXTCA1CA2CA9KCNH2 | |
| SCHEMBL4409731 | 0.72 | IDO1 (0.33) | AGXTCA1IDO1 | |
| SCHEMBL9709126 | 0.71 | ALDH1A1 (0.38) | AGXTIDO1 | |
| SCHEMBL2696466 | 0.70 | CYP1A2 (0.41) | AGXTKCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14478161 | 0.69 | PREP (0.44) | AGXTCA1CA9 | |
| SCHEMBL31389095 | 0.68 | MMP3 (0.40) | IDO1 | |
| SCHEMBL14183641 | 0.68 | KCNH2 (0.42) | AGXTKCNH2IDO1CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206429-A2 | STILBENES WITH VASCULAR DAMAGING ACTIVITY | Angiogene Pharmaceuticals Ltd (GB) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001012579-A2 | NEW STILBENES WITH VASCULAR DAMAGING ACTIVITY | ANGIOGENE PHARMACEUTICALS LTD. (GB) | 2001-02-22 | — | — | WO | disclosed |