Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.39 |
| ▸ | S100A10 | P60903 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786871 | 0.86 | CYP3A4 (0.46) | ALDH1A1PDE7ACYP3A4TP53KDM4E | |
| SCHEMBL7182051 | 0.85 | CYP3A4 (0.60) | ALDH1A1PDE7ACYP3A4TP53KDM4E | |
| SCHEMBL29436321 | 0.83 | CYP3A4 (0.58) | ALDH1A1PDE7ACYP3A4KDM4EMEN1 | |
| SCHEMBL125522 | 0.83 | CYP3A4 (0.58) | ALDH1A1PDE7ACYP3A4KDM4EMEN1 | |
| SCHEMBL16864347 | 0.82 | CYP3A4 (0.56) | ALDH1A1PDE7ACYP3A4TP53KDM4E | |
| Benzene SCHEMBL28782155 | 0.81 | CYP3A4 (0.55) | ALDH1A1PDE7ACYP3A4KDM4EMEN1 | |
| SCHEMBL1100943 | 0.81 | CYP3A4 (0.55) | ALDH1A1PDE7ACYP3A4KDM4EMEN1 | |
| SCHEMBL7190479 | 0.80 | CYP3A4 (0.58) | ALDH1A1PDE7ACYP3A4TP53KDM4E | |
| SCHEMBL1958579 | 0.79 | POLB (0.44) | ALDH1A1CYP3A4KDM4EMEN1HPGD | |
| SCHEMBL1098809 | 0.79 | ANXA2 (0.55) | ALDH1A1PDE7ACYP3A4KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |