Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.36 |
| ▸ | S100A10 | P60903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16864347 | 0.88 | CYP3A4 (0.56) | CYP3A4TP53ALDH1A1TSHRMAPK1 | |
| SCHEMBL7182051 | 0.87 | CYP3A4 (0.60) | CYP3A4TP53ALDH1A1TSHRMAPK1 | |
| SCHEMBL7565404 | 0.86 | ALDH1A1 (0.54) | CYP3A4TP53ALDH1A1MAPTKDM4E | |
| SCHEMBL7190479 | 0.86 | CYP3A4 (0.58) | CYP3A4TP53ALDH1A1TSHRMAPK1 | |
| SCHEMBL28423177 | 0.85 | CHRNA7 (0.46) | TP53CHRNA7ALDH1A1TSHRMAPT | |
| SCHEMBL10362293 | 0.85 | TSHR (0.48) | CYP3A4CHRNA7ALDH1A1TSHRMAPK1 | |
| SCHEMBL3785704 | 0.85 | CHRNA7 (0.46) | TP53CHRNA7ALDH1A1TSHRMAPT | |
| SCHEMBL29215117 | 0.76 | CHRNA7 (0.40) | TP53CHRNA7ALDH1A1MAPTHPGD | |
| SCHEMBL3789926 | 0.76 | MAOA (0.48) | CYP3A4ALDH1A1TSHRMAPK1MAPT | |
| SCHEMBL7185566 | 0.76 | CYP3A4 (0.45) | CYP3A4TP53ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CYP3A4 177/4885TP53 2819/4885CHRNA7 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.