Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.65 |
| ▸ | MAPK13 | O15264 | 18/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 18/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 18/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571478 | 0.89 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7563806 | 0.83 | MAPK13 (0.68) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL2201099 | 0.79 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL7565453 | 0.79 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL7571479 | 0.79 | JAK2 (0.44) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL6652753 | 0.78 | MAPK14 (0.80) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL6654823 | 0.78 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL5989531 | 0.77 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11GAA | |
| SCHEMBL7191939 | 0.77 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL9038897 | 0.76 | GAA (0.46) | MAPK14MAPK13MAPK12MAPK11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | claimed |
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |