SCHEMBL7565573

SCHEMBL7565573

Cc1cc(Br)c(S(=O)(=O)NC(N)=NC(C)C)s1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7592048 0.88 OPRD1 (0.36) LMNAKMT2ASMN1; SMN2
SCHEMBL6807253 0.85 CCR4 (0.40) ALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL7562562 0.79 ALDH1A1 (0.40) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL7565571 0.74 ALDH1A1 (0.32) ALDH1A1LMNAMAPK1MEN1KMT2A
SCHEMBL7561779 0.71 CYP2D6 (0.37) ALDH1A1LMNAMAPK1MEN1KMT2A
SCHEMBL6911509 0.71 MALT1 (0.32) ALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL31487941 0.70 ALDH1A1 (0.41) ALDH1A1LMNAMAPK1
SCHEMBL7563876 0.69 CDK1 (0.45)
SCHEMBL7562558 0.67 CYP2C19 (0.32) ALDH1A1LMNAMAPK1KMT2ASMN1; SMN2
SCHEMBL31488218 0.64 FLT1 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020119969-A1 Novel process NOVO NORDISK A/S (DK) 2002-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119969-A1 Novel process CYP3A5, CYP4F2, CYP4F12 ALDH1A1 267/4885LMNA 4566/4885MAPK1 2799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.