Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637085 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPT | |
| SCHEMBL7481477 | 0.62 | RECQL (0.31) | — | |
| SCHEMBL20458885 | 0.60 | LMNA (0.37) | KDM4EALDH1A1MAPT | |
| SCHEMBL20840303 | 0.56 | LMNA (0.50) | KDM4EALDH1A1MAPT | |
| SCHEMBL737197 | 0.56 | — | — | |
| SCHEMBL4778694 | 0.56 | LMNA (0.50) | KDM4EALDH1A1MAPT | |
| SCHEMBL11916121 | 0.56 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPT | |
| SCHEMBL680281 | 0.56 | LMNA (0.39) | KDM4EALDH1A1MAPT | |
| SCHEMBL21038324 | 0.55 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPT | |
| SCHEMBL3232984 | 0.55 | TSHR (0.36) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252153-A1 | SUBSTITUTED PIPERIDINES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | Boehringer Ingelheim Pharma KG (DE) | 2002-10-30 | — | — | EP | claimed |
| WO-2001049676-A1 | SUBSTITUTED PIPERIDINES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-12 | — | — | WO | claimed |