Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Antergan SCHEMBL94485 | 0.88 | TSHR (0.62) | CHRM2ADRA2ADRD1SLC6A2SLC6A4 | |
| SCHEMBL2103973 | 0.84 | CYP2C19 (0.59) | ADRA2AADRA1ASLC6A3KCNH2ADRA2C | |
| SCHEMBL8015978 | 0.81 | TSHR (0.75) | KDM4ELMNAMAPK1TSHRCYP2C19 | |
| SCHEMBL6555348 | 0.80 | POLB (0.48) | ADRA2AADRA1ASLC6A3KCNH2ADRA2C | |
| SCHEMBL8009515 | 0.80 | NR1H2 (0.51) | KCNH2OPRK1TSHRCYP2C19OPRM1 | |
| SCHEMBL6555897 | 0.78 | TSHR (0.47) | KDM4ELMNAMAPK1SMN1; SMN2TSHR | |
| SCHEMBL11323269 | 0.78 | CNR2 (0.58) | CHRM2ADRA2ADRD1SLC6A2SLC6A4 | |
| SCHEMBL28357225 | 0.77 | TSHR (0.48) | ADRA2AADRA1ASLC6A3KCNH2ADRA2C | |
| SCHEMBL6553725 | 0.77 | TSHR (0.46) | KDM4ELMNAMAPK1SMN1; SMN2TSHR | |
| SCHEMBL863542 | 0.77 | TSHR (0.50) | SLC6A2SLC6A4ADRA1ASLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1234007-A1 | OLIGOMERIC METHINE DYES | Clariant Finance (BVI) Limited (VG) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001036543-A1 | OLIGOMERIC METHINE DYES | CLARIANT FINANCE (BVI) LIMITED (VG) | 2001-05-25 | — | — | WO | disclosed |
| US-4256458-A | DIMERIC PYRIDINIUM DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |