Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PDE6A | P16499 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357225 | 0.88 | TSHR (0.48) | CYP2C19TSHRNR1H2NR1H3CYP2D6 | |
| SCHEMBL8015978 | 0.88 | TSHR (0.75) | CYP2C19TSHRNR1H2NR1H3TAAR1 | |
| SCHEMBL6554158 | 0.85 | TSHR (0.46) | CYP2C19TSHRNR1H2NR1H3CYP2D6 | |
| SCHEMBL7838397 | 0.85 | SLC6A2 (0.51) | CYP2C19TSHRCYP2D6CYP1A2SLC6A3 | |
| SCHEMBL7565830 | 0.84 | CHRM2 (0.53) | CYP2C19TSHRCYP2D6TAAR1LMNA | |
| SCHEMBL6555348 | 0.84 | POLB (0.48) | CYP2C19TSHRCYP2D6TAAR1LMNA | |
| SCHEMBL2960872 | 0.84 | CYP2C19 (0.78) | CYP2C19TSHRNR1H2NR1H3CYP2D6 | |
| SCHEMBL43183 | 0.84 | TSHR (0.74) | CYP2C19TSHRNR1H2NR1H3CYP2D6 | |
| Hydrochloric Acid SCHEMBL2139953 | 0.81 | TSHR (0.71) | CYP2C19TSHRNR1H2NR1H3CYP2D6 | |
| SCHEMBL355040 | 0.81 | TSHR (0.71) | CYP2C19TSHRNR1H2NR1H3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777148-B2 | CHARGE-TRANSPORTING MATERIAL IN A PHOTOSENSITIVE LAYER OF AN ELECTROPHOTOGRAPHIC PHOTORECEPTOR OR USABLE IN VARIOUS DISPLAY DEVICES, AND AN ELECTROPHOTOGRAPHIC PHOTORECEPTOR WHICH USES THE ABOVE ORGANIC PHOTOCONDUCTIVE MATERIAL IN A | MITSUBISHI PAPER MILLS LIMITED (JP) | 2004-08-17 | — | — | US | claimed |
| US-20030148201-A1 | Organic photoconductive material and electrophotographic photoreceptor using the material | HODOGAYA CHEMICAL CO., LTD. (JP) | 2003-08-07 | — | — | US | claimed |
| US-5492792-A | OPTICAL CARD OR DISKS; EXCELLENT LIGHT SENSITIVITY WITHIN NEAR INFRARED REGION AND HEAT RESISTANCE; STORE INFORMATIONSAT HIGH DENSITY | CANON KABUSHIKI KAISHA (JP) | 1996-02-20 | — | — | US | claimed |
| US-4891305-A | LASERS | RICOH CO., LTD. (JP) | 1990-01-02 | — | — | US | claimed |
| US-4859556-A | MULTILAYER; ELECTROCONDUCTIVE SUPPORT WITH PHOTOSENSITIVE MATERIAL | RICOH COMPANY, LTD. (JP) | 1989-08-22 | — | — | US | claimed |
| US-4454211-A | Electrophotographic photosensitive member with pyrazoline charge transport material | CANON KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | claimed |
| US-4420548-A | Electrophotographic member with hydrazone or ketazine compounds | CANON KABUSHIKI KAISHA (JP) | 1983-12-13 | — | — | US | claimed |
| JP-55021080-A | — | — | None | — | — | JP | disclosed |
| CN-102850728-B | Doped conjugated polymers, devices, and methods of making devices | SANYO CHEMICAL IND LTD | 2015-07-22 | — | — | CN | disclosed |
| CN-104204009-A | Dioxaborinane co-polymers and uses thereof | EMPIRE TECHNOLOGY DEV LLC | 2014-12-10 | — | — | CN | disclosed |
| US-8772507-B2 | Imidazole-benzamide anti-cancer agents | CYTOKINETICS, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| EP-2637656-A1 | PIPERIDINONE CARBOXAMIDE INDANE CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2013-09-18 | — | — | EP | disclosed |
| US-20130096315-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | QIAN XIANGPING (US) | 2013-04-18 | — | — | US | disclosed |
| US-4343944-A | Indolinospiropyrane compounds | CIBA-GEIGY CORPORATION (US) | 1982-08-10 | — | — | US | disclosed |
| US-4339385-A | Indolinospiropyrane compounds | CIBA-GEIGY CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| US-4281855-A | Pressure-sensitive or heat-sensitive recording material and novel 2,2-diarylchromeno compounds used therein | CIBA-GEIGY CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4256458-A | DIMERIC PYRIDINIUM DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4210591-A | Indolinospiropyrane compounds | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| JP-S5521080-A | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | RICOH CO LTD | 1980-02-14 | — | — | JP | disclosed |
| US-4187233-A | Pressure-sensitive or heat-sensitive recording material and novel 2,2-diarylchromeno compounds used therein | CIBA-GEIGY CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030148201-A1 | Organic photoconductive material and electrophotographic photoreceptor using the material | ALDH1A2, NR2E3, PDE6C | CYP2C19 3892/4885TSHR 4758/4885NR1H2 3524/4885 |
| US-20130096315-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | KIF5B, KIF2C, PLK1 | CYP2C19 4805/4885TSHR 4746/4885NR1H2 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.