Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571221 | 0.82 | IDO1 (0.46) | IDO1ALDH1A1MAPTL3MBTL1CTSL | |
| SCHEMBL7564705 | 0.82 | IDO1 (0.46) | IDO1ALDH1A1MAPTL3MBTL1CTSL | |
| SCHEMBL11118986 | 0.78 | IDO1 (0.46) | IDO1ALDH1A1MAPTL3MBTL1CTSL | |
| SCHEMBL7565981 | 0.75 | IDO1 (0.52) | IDO1ALDH1A1MAPTL3MBTL1CTSL | |
| SCHEMBL13783987 | 0.75 | IDO1 (0.50) | IDO1ALDH1A1MAPTL3MBTL1CCKAR | |
| SCHEMBL31758027 | 0.74 | DRD2 (0.41) | IDO1ALDH1A1MAPTCTSL | |
| SCHEMBL31757665 | 0.74 | DRD2 (0.41) | IDO1ALDH1A1MAPTCTSL | |
| SCHEMBL18815112 | 0.72 | IDO1 (0.40) | IDO1ALDH1A1MAPTCTSLEPHX2 | |
| SCHEMBL30693758 | 0.69 | IDO1 (0.82) | IDO1CCKARCCKBRTDO2 | |
| SCHEMBL27349526 | 0.69 | IDO1 (0.82) | IDO1CCKARCCKBRTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |