Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31758027 | 0.83 | DRD2 (0.41) | IDO1SCN9ACTSLCTSKCTSB | |
| SCHEMBL31757665 | 0.83 | DRD2 (0.41) | IDO1SCN9ACTSLCTSKCTSB | |
| SCHEMBL7571221 | 0.83 | IDO1 (0.46) | IDO1EPHX2CCKARCCKBRCTSL | |
| SCHEMBL7565993 | 0.82 | IDO1 (0.52) | IDO1CALCRLEPHX2CCKARCCKBR | |
| SCHEMBL7567176 | 0.81 | EPHX2 (0.53) | IDO1EPHX2SCN9ACTSLSMYD3 | |
| SCHEMBL11118986 | 0.79 | IDO1 (0.46) | IDO1SCN9ACCKARCCKBRCTSL | |
| SCHEMBL7543362 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11118093 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15414265 | 0.77 | SCN9A (0.47) | IDO1EPHX2SCN9A | |
| SCHEMBL15414268 | 0.77 | SCN9A (0.47) | IDO1EPHX2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |