Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566375 | 0.86 | RAD52 (0.51) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7566364 | 0.85 | RAD52 (0.45) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL8411531 | 0.84 | RAD52 (0.42) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7566368 | 0.84 | RAD52 (0.42) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL7564150 | 0.83 | RAD52 (0.51) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL8415115 | 0.81 | RAD52 (0.52) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL31399388 | 0.81 | RAD52 (0.55) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL626969 | 0.81 | RAD52 (0.55) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL29406087 | 0.81 | RAD52 (0.55) | RAD52SMARCA2MAPTCYP1A2CYP2C9 | |
| SCHEMBL8414094 | 0.79 | AOX1 (0.47) | RAD52MAPTNQO2KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |