Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 15/20 | 0.52 |
| ▸ | ACE | P12821 | 11/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567834 | 0.89 | MME (0.50) | MMEACECPA1ACE2MAPK1 | |
| SCHEMBL7572397 | 0.89 | ACE (0.51) | MMEACECPA1ACE2 | |
| SCHEMBL7570085 | 0.88 | MME (0.47) | MMEACEFFAR1FFAR4 | |
| SCHEMBL7567661 | 0.88 | MME (0.49) | MMEACEFFAR1FFAR4CPA1 | |
| SCHEMBL7575117 | 0.88 | MME (0.49) | MMEACECPA1ACE2 | |
| SCHEMBL7568664 | 0.86 | MME (0.49) | MMEACECPA1ACE2ITGB2 | |
| SCHEMBL7567107 | 0.84 | MME (0.46) | MMEACECPA1ACE2ITGA4 | |
| SCHEMBL7565255 | 0.80 | MME (0.69) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL7573605 | 0.78 | MME (0.47) | MMEACE | |
| SCHEMBL7567517 | 0.78 | MME (0.77) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |