Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.47 |
| ▸ | ACE | P12821 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573605 | 0.91 | MME (0.47) | MMEACECTSB | |
| SCHEMBL7573789 | 0.90 | MME (0.46) | MMEACECTSB | |
| SCHEMBL7573305 | 0.90 | MME (0.45) | MMEACECTSBGPR34FFAR1 | |
| SCHEMBL7565209 | 0.89 | MME (0.46) | MMEACECTSB | |
| SCHEMBL7566385 | 0.88 | MME (0.52) | MMEACEFFAR1FFAR4 | |
| SCHEMBL7565217 | 0.87 | ITGA4 (0.44) | MMEACECTSB | |
| SCHEMBL7567698 | 0.84 | MME (0.59) | MMEACECTSBGPR34 | |
| SCHEMBL7574613 | 0.83 | MME (0.55) | MMEACECTSBGPR34 | |
| SCHEMBL7574618 | 0.83 | MME (0.55) | MMEACECTSBGPR34 | |
| SCHEMBL7568360 | 0.82 | MME (0.66) | MMEACECTSBGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |