Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.49 |
| ▸ | ACE | P12821 | 8/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565209 | 0.89 | MME (0.46) | MMEACELPAR1ALDH1A1ALOX15 | |
| SCHEMBL7567834 | 0.87 | MME (0.50) | MMEACECPA1ACE2LPAR1 | |
| SCHEMBL7572397 | 0.87 | ACE (0.51) | MMEACECPA1ACE2LPAR1 | |
| SCHEMBL7575117 | 0.86 | MME (0.49) | MMEACECPA1ACE2LPAR1 | |
| SCHEMBL7567661 | 0.86 | MME (0.49) | MMEACECPA1ACE2LPAR1 | |
| SCHEMBL7566385 | 0.86 | MME (0.52) | MMEACECPA1ACE2ITGB2 | |
| SCHEMBL7567107 | 0.83 | MME (0.46) | MMEACECPA1ACE2ITGB2 | |
| SCHEMBL7573605 | 0.79 | MME (0.47) | MMEACELPAR1CTSB | |
| SCHEMBL7565255 | 0.78 | MME (0.69) | MMEACECPA1ACE2CTSB | |
| SCHEMBL7573789 | 0.78 | MME (0.46) | MMEACELPAR1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |