Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566106 | 0.88 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7568203 | 0.88 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7567373 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL7568644 | 0.82 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL7567359 | 0.82 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL7569123 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7566413 | 0.77 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL7572803 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7491502 | 0.71 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL7567376 | 0.71 | PTGS2 (0.79) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889878-B1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2002-09-04 | — | — | EP | claimed |
| US-5817700-A | ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1998-10-06 | — | — | US | claimed |
| EP-0889878-B1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2002-09-04 | — | — | EP | disclosed |
| EP-0889878-A1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1999-01-13 | — | — | EP | disclosed |
| US-5817700-A | ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1998-10-06 | — | — | US | disclosed |
| WO-1997036863-A1 | BISARYLCYCLOBUTENE DERIVATES AS CYCLOOXYGENASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-10-09 | — | — | WO | disclosed |