Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 3/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415079 | 0.94 | RAD52 (0.50) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL8009925 | 0.86 | HPGD (0.49) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL7565910 | 0.85 | RAD52 (0.55) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL8013625 | 0.84 | RAD52 (0.47) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL7998025 | 0.84 | RAD52 (0.47) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL8415115 | 0.83 | RAD52 (0.52) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL7570872 | 0.82 | RAD52 (0.51) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL14440022 | 0.82 | RAD52 (0.51) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL29406087 | 0.82 | RAD52 (0.55) | CYP1A2MAPTCYP2C9CYP2C19RAD52 | |
| SCHEMBL626969 | 0.82 | RAD52 (0.55) | CYP1A2MAPTCYP2C9CYP2C19RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |