Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009925 | 0.96 | HPGD (0.49) | RAD52HPGDSMARCA2KDM4ELMNA | |
| SCHEMBL7567038 | 0.86 | RAD52 (0.57) | RAD52HPGDSMARCA2LMNASIGMAR1 | |
| SCHEMBL7573617 | 0.85 | HDAC1 (0.49) | RAD52HPGDKDM4ELMNAPOLB | |
| SCHEMBL8415079 | 0.84 | RAD52 (0.50) | RAD52HPGDSMARCA2HDAC1HDAC6 | |
| SCHEMBL7573723 | 0.84 | RAD52 (0.46) | RAD52SMARCA2HDAC1HDAC6MAPT | |
| SCHEMBL8414078 | 0.84 | RAD52 (0.46) | RAD52SMARCA2HDAC1HDAC6MAPT | |
| SCHEMBL7568056 | 0.83 | RAD52 (0.61) | RAD52HPGDSMARCA2LMNAPOLB | |
| SCHEMBL7566449 | 0.82 | CYP1A2 (0.51) | RAD52HPGDSMARCA2HDAC1HDAC6 | |
| SCHEMBL7567001 | 0.82 | SIGMAR1 (0.56) | RAD52HPGDSMARCA2KDM4ELMNA | |
| SCHEMBL7998025 | 0.80 | RAD52 (0.47) | RAD52HPGDSMARCA2KDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |