SCHEMBL7998025

SCHEMBL7998025

CNCCCNC(=O)c1cccc2nc3ccc(C)cc3nc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 3/20 0.47
MAPT P10636 4/20 0.46
CYP1A2 P05177 3/20 0.46
CYP2C9 P11712 3/20 0.46
CYP2C19 P33261 3/20 0.46
SMARCA2 P51531 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
AOX1 Q06278 1/20 0.43
NQO2 P16083 1/20 0.42
ALDH1A1 P00352 4/20 0.42
NPSR1 Q6W5P4 3/20 0.42
KDM4E B2RXH2 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TSHR P16473 2/20 0.42
GLA P06280 2/20 0.42
HPGD P15428 2/20 0.42
CASP1 P29466 2/20 0.42
HSD17B10 Q99714 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8013625 1.00 RAD52 (0.47) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL8414078 0.88 RAD52 (0.46) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL7573723 0.88 RAD52 (0.46) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL7566551 0.87 RAD52 (0.53) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL7568883 0.87 RAD52 (0.53) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL7566449 0.84 CYP1A2 (0.51) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL8415079 0.83 RAD52 (0.50) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL8009925 0.81 HPGD (0.49) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL7570872 0.80 RAD52 (0.51) RAD52MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL7568056 0.78 RAD52 (0.61) RAD52MAPTSMARCA2NQO2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114332-A BACTERICIDES XENOVA LIMITED (GB) 2000-09-05 US disclosed