Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 6/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043090 | 0.86 | REN (0.41) | KMT2AMEN1RENLTA4HKDM4E | |
| SCHEMBL6042315 | 0.82 | KDM4E (0.38) | KMT2AMEN1RENKDM4EALDH1A1 | |
| SCHEMBL6042310 | 0.79 | REN (0.46) | KMT2AMEN1RENKDM4EALDH1A1 | |
| SCHEMBL6952826 | 0.77 | REN (0.36) | KMT2AMEN1RENKDM4EALDH1A1 | |
| SCHEMBL6043145 | 0.72 | REN (0.51) | KMT2ARENKDM4EALDH1A1LMNA | |
| SCHEMBL6043150 | 0.72 | REN (0.51) | KMT2ARENKDM4EALDH1A1LMNA | |
| SCHEMBL6042685 | 0.72 | REN (0.49) | RENKDM4EALDH1A1LMNA | |
| SCHEMBL6042682 | 0.72 | REN (0.49) | RENKDM4EALDH1A1LMNA | |
| SCHEMBL13778710 | 0.72 | DRD2 (0.54) | KMT2AMEN1LMNAGAA | |
| SCHEMBL6042041 | 0.72 | REN (0.45) | KMT2AMEN1RENKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |