Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433982 | 0.81 | ATM (0.33) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL7568426 | 0.81 | MAPT (0.39) | CYP2C9CYP2C19LMNA | |
| SCHEMBL438903 | 0.79 | SLC1A2 (0.42) | L3MBTL1 | |
| SCHEMBL12221733 | 0.73 | ATM (0.51) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL18211321 | 0.72 | ATM (0.46) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL6663654 | 0.71 | TSHR (0.33) | TSHRCYP2C19 | |
| SCHEMBL379399 | 0.69 | GAA (0.37) | L3MBTL1 | |
| SCHEMBL1231230 | 0.68 | GAA (0.47) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL30318888 | 0.67 | ATM (0.41) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL30672664 | 0.67 | ATM (0.41) | ATML3MBTL1CYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233989-A2 | INHIBITION OF POLYMERIZATION OF UNSATURATED MONOMERS | Crompton Corporation (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001040319-A2 | INHIBITION OF POLYMERIZATION OF UNSATURATED MONOMERS | CROMPTON CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |