Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936712 | 0.83 | MAPT (0.37) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7566570 | 0.81 | ATM (0.40) | CYP2C9CYP2C19LMNA | |
| SCHEMBL438903 | 0.75 | SLC1A2 (0.42) | ALDH1A1 | |
| SCHEMBL16751016 | 0.71 | MAPT (0.38) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12846027 | 0.71 | GAA (0.42) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3057229 | 0.70 | SLC18A2 (0.30) | — | |
| SCHEMBL16149731 | 0.70 | LMNA (0.43) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1813544 | 0.69 | CYP3A4 (0.44) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL294716 | 0.69 | LMNA (0.43) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11816878 | 0.69 | LMNA (0.38) | MAPTPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233989-A2 | INHIBITION OF POLYMERIZATION OF UNSATURATED MONOMERS | Crompton Corporation (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001040319-A2 | INHIBITION OF POLYMERIZATION OF UNSATURATED MONOMERS | CROMPTON CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |