SCHEMBL1433982

SCHEMBL1433982

COC(=O)C1CC(C)(C)N([O])C1(C)C

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
GAA P10253 1/20 0.32
CYP1A2 P05177 2/20 0.32
HIF1A Q16665 1/20 0.32
TSHR P16473 2/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLB P06746 1/20 0.30
BRD4 O60885 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231230 0.82 GAA (0.47) ATMLMNAL3MBTL1GAACYP1A2
SCHEMBL7566570 0.81 ATM (0.40) ATMLMNAL3MBTL1CYP1A2HIF1A
SCHEMBL21102900 0.81 CYP1A2 (0.35) ATMLMNAL3MBTL1GAACYP1A2
Hydrochloric Acid SCHEMBL9993297 0.81 GAA (0.45) ATMLMNAL3MBTL1GAACYP1A2
SCHEMBL7936712 0.80 MAPT (0.37) LMNACYP3A4MAPTCYP2C9CYP2C19
SCHEMBL3057229 0.80 SLC18A2 (0.30)
SCHEMBL475361 0.78 APLNR (0.38) L3MBTL1GAACYP1A2KMT2AMEN1
SCHEMBL9754770 0.78 GAA (0.31) L3MBTL1GAA
SCHEMBL3169577 0.78
SCHEMBL932260 0.77 ADAM17 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1178026-B1 PROCESSES FOR PRODUCING OXIDE WITH HIGHER OXIDATION THAN ALCOHOL OTSUKA KAGAKU KK (JP) 2011-03-30 EP claimed
EP-4397755-A2 DELIVERY OF THERAPEUTIC AGENTS BY A COLLAGEN BINDING PROTEIN The Board of Trustees of the University of Arkansas (US) 2024-07-10 EP disclosed
EP-3808365-B1 DELIVERY OF THERAPEUTIC AGENTS BY A COLLAGEN BINDING PROTEIN UNIV ARKANSAS (US) 2024-01-31 EP disclosed
WO-2022210565-A1 DNP-MRI SYSTEM, DEVICE, AND CONTROL METHOD, AND INFORMATION DERIVATION METHOD AND DIAGNOSTIC METHOD EMPLOYING DNP-MRI SYSTEM 国立大学法人東海国立大学機構 2022-10-06 WO disclosed
US-11279922-B2 Delivery of therapeutic agents by a collagen binding protein THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2022-03-22 US disclosed
EP-3671217-A1 INVENTION RELATING TO DIAGNOSIS OF TRANSPLANT REJECTION Justus-Liebig-Universität Gießen (DE) 2020-06-24 EP disclosed
EP-1178026-B1 PROCESSES FOR PRODUCING OXIDE WITH HIGHER OXIDATION THAN ALCOHOL OTSUKA KAGAKU KK (JP) 2011-03-30 EP disclosed
US-7183421-B2 Processes for producing oxide with higher oxidation than alcohol OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2007-02-27 US disclosed
US-20050014957-A1 Processes for producing oxide with higher oxidation than alcohol TANAKA HIDEO (JP) 2005-01-20 US disclosed
US-6797830-B2 SILICA GEL CARRIES AN ALCOHOL AND AN OXIDATIVE CATALYST AND OXIDIZING THE ALCOHOL IN THE PRESENCE OF AN OXIDIZER OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2004-09-28 US disclosed
US-20030114712-A1 Process for producing oxide with higher oxidation than alcohol OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2003-06-19 US disclosed
EP-1186588-A1 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2002-03-13 EP disclosed
EP-1178026-A1 PROCESSES FOR PRODUCING OXIDE WITH HIGHER OXIDATION THAN ALCOHOL OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2002-02-06 EP disclosed
US-6239145-B1 USABLE IN ACQUIRING INFORMATION ABOUT ACTIVE OXYGEN OR IN VIVO FREE RADICALS AS BIOLOGICAL IMAGES SUCH AS MAGNETIC RESONANCE IMAGES OR MAGNETOENCEPHALOGRAMS; DAIITCHI RADIOISOTOPE LABORATORIES, LTD. (JP) 2001-05-29 US disclosed
EP-0995740-A1 NOVEL NITROXYL COMPOUNDS AND DRUGS AND REAGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) 2000-04-26 EP disclosed
US-4925652-A NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
US-4845090-A NUCLEAR MAGNETIC RESONANCE SCHERING AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014957-A1 Processes for producing oxide with higher oxidation than alcohol ADH1A, NOX4, AOX1 ATM 1140/4885LMNA 2655/4885L3MBTL1 4784/4885
US-11279922-B2 Delivery of therapeutic agents by a collagen binding protein PTH1R, GHRHR, FGF23 ATM 4050/4885LMNA 1440/4885L3MBTL1 3567/4885
US-20030114712-A1 Process for producing oxide with higher oxidation than alcohol ADH1A, NOX4, AOX1 ATM 1126/4885LMNA 2690/4885L3MBTL1 4802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.