Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448034 | 0.91 | ALDH1A1 (0.71) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL7569010 | 0.91 | ALDH1A1 (0.58) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL5457153 | 0.90 | ALDH1A1 (0.69) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL30548734 | 0.87 | ALDH1A1 (0.88) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL68995 | 0.87 | ALDH1A1 (0.88) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL8520023 | 0.85 | ALDH1A1 (0.63) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL7567602 | 0.84 | ALDH1A1 (0.61) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL3557070 | 0.82 | ALDH1A1 (0.68) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL30380388 | 0.82 | ALDH1A1 (0.68) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 | |
| Phenazine-1-Carboxylic Acid SCHEMBL27752237 | 0.82 | ALDH1A1 (0.93) | ALDH1A1CYP2C9CYP1A2MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |