Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566595 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTCYP2C9CYP1A2 | |
| SCHEMBL5457153 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTMAPK1CYP2C9 | |
| SCHEMBL5886249 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTCYP2C9CYP1A2 | |
| SCHEMBL5448034 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTMAPK1CYP2C9 | |
| SCHEMBL68995 | 0.79 | ALDH1A1 (0.88) | ALDH1A1KDM4EMAPTCYP2C9CYP1A2 | |
| SCHEMBL30548734 | 0.79 | ALDH1A1 (0.88) | ALDH1A1KDM4EMAPTCYP2C9CYP1A2 | |
| SCHEMBL30380388 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTCYP2C9CYP1A2 | |
| SCHEMBL3557070 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTCYP2C9CYP1A2 | |
| Phenazine-1-Carboxylic Acid SCHEMBL27752237 | 0.78 | ALDH1A1 (0.93) | ALDH1A1KDM4EMAPTCYP2C9CYP1A2 | |
| SCHEMBL8411675 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP2C9CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |